Article

Live-Attenuated CHIKV Vaccine with Rearranged Genome Replicates <i>in vitro</i> and Induces Immune Response in Mice

2023-09-16

Abstract excerpt

<h4>ABSTRACT</h4> Chikungunya fever virus (CHIKV) is a mosquito-borne alphavirus that causes wide-spread human infections and epidemics in Asia, Africa and recently, in the Americas. There is no approved vaccine and CHIKV is considered a priority pathogen by CEPI and WHO. Previously, we developed immunization DNA (iDNA) plasmid capable of launching live-attenuated CHIKV vaccine in vivo . Here we report the use o...

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Literature Corpus work: 09951527-7e2e-5f39-a864-495cbd0d403e
DOI: 10.1101/2023.09.16.558061

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