Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel attenuated Chikungunya vaccine candidates elicit protective immunity in C57BL/6 mice.

Journal of virology - 1 Mar 2014

Hallengärd David, Kakoulidou Maria, Lulla Aleksei, Kümmerer Beate M, Johansson Daniel X, Mutso Margit, Lulla Valeria, Fazakerley John K, Roques Pierre, Le Grand Roger, Merits Andres, Liljeström Peter

Abstract excerpt

UNLABELLED: Chikungunya virus (CHIKV) is a reemerging mosquito-borne alphavirus that has caused severe epidemics in Africa and Asia and occasionally in Europe. As of today, there is no licensed vaccine available to prevent CHIKV infection. Here we describe the development and evaluation of novel CHIKV vaccine candidates that were attenuated by deleting a large part of the gene encoding nsP3 or the entire gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alphavirus Infections
Share to Chikungunya Fever

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chikungunya virus

Share to Immunity, Cellular

Share to Immunization

Share to Immunization, Secondary

Share to Vaccines, Attenuated

Share to Viral Vaccines

Source

Open in PubMed Open full text

Identifiers

PMID: 24371047
DOI: 10.1128/JVI.03453-13
PMCID: PMC3958085

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel attenuated Chikungunya vaccine candidates elicit protective immunity in C57BL/6 mice.PMID 24371047Read ↗

Enhanced attenuation of chikungunya vaccines expressing antiviral cytokinesSemantic proximity Read ↗

Attenuated and vectored vaccines protect nonhuman primates against Chikungunya virusSemantic proximity Read ↗

Infectious RNA vaccine protects mice against chikungunya virus infection.Semantic proximity Read ↗

Chikungunya virus vaccine: a decade of progress solving epidemiological dilemma, emerging concepts, and immunological interventionsSemantic proximity Read ↗

Evolution and immunopathology of chikungunya virus informs therapeutic development.Semantic proximity Read ↗

Chimeric Chikungunya Viruses Are Nonpathogenic in Highly Sensitive Mouse Models but Efficiently Induce a Protective Immune ResponseSemantic proximity Read ↗

Chikungunya Virus Vaccine Candidates with Decreased Mutational Robustness Are AttenuatedIn Vivoand Have Compromised TransmissibilitySemantic proximity Read ↗

Chikungunya virus host range E2 transmembrane deletion mutants induce protective immunity against challenge in C57BL/6J mice.Semantic proximity Read ↗

Attenuation of Chikungunya Virus by a Single Amino Acid Substitution in the nsP1 Component of a Non-Structural PolyproteinSemantic proximity Read ↗

Construction and immunogenicity of an mRNA vaccine against chikungunya virusSemantic proximity Read ↗

Chimeric alphavirus vaccine candidates for chikungunyaSemantic proximity Read ↗

A Virus-Like Particle Vaccine Elicits Broad Neutralizing Antibody Responses in Humans to All Chikungunya Virus Genotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.