Article
For Better or Worse: Modulation of the Host DNA Damage Response by Human Papillomavirus
11 Apr 2023
Abstract excerpt
High-risk human papillomaviruses (HPVs) are associated with several human cancers. HPVs are small, DNA viruses that rely on host cell machinery for viral replication. The HPV life cycle takes place in the stratified epithelium, which is composed of different cell states, including terminally differentiating cells that are no longer active in the cell cycle. HPVs have evolved mechanisms to persist and replicate in...
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