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<i>Helicobacter pylori</i> infection and α-synuclein pathology drive parallel neurodegenerative pathways in the substantia nigra

2025-08-30

Abstract excerpt

<h4>ABSTRACT</h4> Parkinson’s disease is a common neurodegenerative disease related to both genetic and environmental insults. Epidemiological studies have linked Helicobacter pylori (H. pylori ) infection to Parkinson’s disease risk, but the underlying mechanisms of this association remain unclear. In this study, we investigate whether chronic infection with a pathogenic H. pylori strain can induce α-synuclein...

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Literature Corpus work
0979b30c-69e8-5cc9-9f60-9eb45b2bc3c5
DOI
10.1101/2025.08.26.672190
Open publication

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