Article

RNA-Seq analysis of early transcriptional responses to activation in the leukaemic Jurkat E6.1 T cell line

2021-06-17

Abstract excerpt

<h4>Background: </h4> The leukaemia-derived Jurkat E6.1 cell line has been used as a model T cell in the study of many aspects of T cell biology, most notably activation in response to T cell receptor (TCR) engagement. <h4>Methods: </h4>: We present whole-transcriptome RNA-Sequencing data for Jurkat E6.1 cells in the resting state and two hours post-activation via TCR and CD28. We compare early transcriptional re...

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Literature Corpus work: 0932a0f2-a380-55a2-9f5c-ae4176cb91f9
DOI: 10.12688/wellcomeopenres.15748.2

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