Back to search

Article

Population-associated molecular variation in histologically normal breast tissue is context-dependent and associated with distinct transcriptional states

2026-06-18

Abstract excerpt

Population-associated molecular variation in breast tissue may contribute to differences in tissue biology and disease susceptibility, yet the extent to which such variation is shaped by underlying tissue states remains unclear. Here, we performed RNA-seq and lipidomic profiling of histologically normal breast tissue samples from African American (AA) and Caucasian White (CW) individuals, followed by conceptual in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
092b5435-3bbf-5ba2-8892-117b2e9302cc
DOI
10.64898/2026.06.16.732684
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Population-associated molecular variation in histologically normal breast tissue is context-dependent and associated with distinct transcriptional statesDOI 10.64898/2026.06.16.732684
A spatially resolved single cell genomic atlas of the adult human breastSemantic proximity
Adipose-enriched peri-tumoral stroma, in contrast to myofibroblast-enriched stroma, prognosticates poorer survival in breast cancersSemantic proximity
Platform Biological Divergence: quantifying gene-level differences between bulk and single-cell transcriptomics in breast cancerSemantic proximity
Characterization of four subtypes in morphologically normal tissue excised proximal and distal to breast cancerSemantic proximity
Mapping lineage and functional diversity in the high-risk human mammary epitheliumSemantic proximity
A risk-associated Active transcriptome phenotype expressed by histologically normal human breast tissue and linked to a pro-tumorigenic adipocyte population.Semantic proximity
Mapping lineage and functional diversity of the mammary epithelium in women at high risk of breast cancerSemantic proximity
Ancestry-associated transcriptomic profiles of breast cancer in patients of African, Arab, and European ancestrySemantic proximity
Proteomic analysis of archival breast cancer clinical specimens identifies biological subtypes with distinct survival outcomesSemantic proximity
MiXcan: a framework for cell-type-aware transcriptome-wide association studies with an application to breast cancer.Semantic proximity
Spatial Proteomics of the Normal Breast Collagen Stroma: Links to BI-RADS Categories and Body Mass IndexSemantic proximity
Breast tumor microenvironment structures are associated with genomic features and clinical outcomeSemantic proximity
Select a neighboring publication to make it the new centre.