Article

Mapping lineage and functional diversity of the mammary epithelium in women at high risk of breast cancer

2026-08-14

Abstract excerpt

Breast cancer risk is shaped by the vast heterogeneity of mammary epithelial cells, comprising basal, luminal progenitor, and mature luminal populations. While transcriptional variation among these lineages has been extensively studied, protein-level features—particularly in high-risk women—remain underexplored, limiting insight into early cellular and molecular determinants of susceptibility. Moreover, little is...

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Literature Corpus work: 06dfaed6-6436-572d-b05e-aa5c81868e35
DOI: 10.1186/s13059-026-04243-3

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