Article

AKR1C3 Expression in T and B Acute Lymphoblastic Leukemia/Lymphoma for Clinical Use as a Biomarker

2021-11-03

Abstract excerpt

<h4>Objectives: </h4> To investigate aldo–keto reductase 1C3 (AKR1C3) expression in T and B acute lymphoblastic leukemia/lymphoma (ALL) patients. <h4>Methods: </h4>: Three commercial antibodies were evaluated for AKR1C3 immunohistochemistry (IHC) staining performance: Polyclonal Thermofisher scientific (Clone#PA523667), rabbit monoclonal Abcam [EPR16726] (ab209899) and Sigma/Millipore anti-AKR1C3 antibody, mouse m...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 09143d9d-e0fb-5f19-8394-651e3b9e44f7
DOI: 10.21203/rs.3.rs-1009027/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

AKR1C3 Expression in T and B Acute Lymphoblastic Leukemia/Lymphoma for Clinical Use as a BiomarkerDOI 10.21203/rs.3.rs-1009027/v1Read

AKR1C3 expression in T acute lymphoblastic leukemia/lymphoma for clinical use as a biomarkerSemantic proximity Read

AKR1C3 is a biomarker of sensitivity to PR-104 in preclinical models of T-cell acute lymphoblastic leukemiaSemantic proximity Read

AKR1C enzymes sustain therapy resistance in paediatric T-ALLSemantic proximity Read

AKR1C3 is a biomarker and druggable target for oropharyngeal tumorsSemantic proximity Read

Identification and validation of AKR1C1/2/3 as hepatocellular carcinoma risk modules via an integrated strategySemantic proximity Read

Adult B-Cell Acute Lymphoblastic Leukaemia Antigens and Enriched Pathways Identify New Targets for TherapySemantic proximity Read

Harnessing ALDH1A2 vulnerability in T-cell acute lymphoblastic leukemiaSemantic proximity Read

Establishment and chacterization of a novel cell line ICH-BCPALL-3 from B-cell precursor acute lymphoblastic leukemia with TCF3::HLF.Semantic proximity Read

An alternative CYB5A transcript is expressed in aneuploid ALL and enriched in relapse.Semantic proximity Read

Effect of ABCB1 Expression on Measurable Residual Disease in Adult Patients with Acute Lymphoblastic LeukemiaSemantic proximity Read

PHi-RACE: PGIMER in-house rapid & cost effective classifier for the detection of BCR-ABL1 -like acute lymphoblastic leukaemia in Indian patientsSemantic proximity Read

BRD4 PROTAC Degrader ARV-825 Inhibits T-Cell Acute Lymphoblastic Leukemia by Targeting 'Undruggable' Myc-pathway GenesSemantic proximity Read