Article

Cell-density independent increased lymphocyte production and loss rates post-autologous hematopoietic stem cell transplantation

2020-04-29

Abstract excerpt

Lymphocyte numbers need to be quite tightly regulated. It is generally assumed that lymphocyte production and survival rates increase homeostatically when lymphocyte numbers decrease. This widely-accepted concept is largely based on experiments in mice. In humans, lymphocyte reconstitution usually occurs very slowly, which challenges the idea that density dependent homeostasis aids recovery from lymphopenia. Using...

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Literature Corpus work: 08e8bb9e-1ed8-5ea6-8313-0d4d6a4d84b7
DOI: 10.1101/2020.04.24.20078295

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