Article

Duchenne muscular dystrophy is driven by defective membrane repair and annexin-A2 dysregulation in skeletal muscle

2025-09-23

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Duchenne muscular dystrophy (DMD) is caused by mutations in the DMD gene, which encodes dystrophin in skeletal muscle cells. Although the role of dystrophin as a structural protein is well known, the cellular processes underlying myofiber degeneration are still not fully understood. Despite advances from studies in murine models, these models do not fully replicate the huma...

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Literature Corpus work: 08e3fd8a-6e7f-59d2-9d47-7782db23375a
DOI: 10.1101/2025.09.23.677988

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