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Article

Membrane Injury and Repair in the Muscular Dystrophies

18 Nov 2014

Abstract excerpt

Muscle cells have an elaborate plasma membrane and t-tubule system that has been evolutionarily refined to maximize electrical conductivity for synchronous muscle contraction. However, this elaborate plasma membrane network has intrinsic vulnerabilities to stretch-induced membrane injury, and thus requires ongoing maintenance and repair. Herein we discuss the types of membrane injuries encountered by myofibers in...

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Identifiers

PMID: 25406223
DOI: 10.1177/1073858414558336

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