Article

Targeted Immune Epitope Prediction to HHLA2 and MAGEB5 Protein Variants as Therapeutic Approach to Related Viral Diseases.

2021-01-25

Abstract excerpt

<h4>Background: </h4> Targeted immunotherapy is mostly associated with cancer treatment wherein designed molecules engage signaling pathways and mutant proteins critical to the survival of the cell. One of several genetic approaches is the use of in silico methods to develop immune epitopes targeting specific antigenic regions on related mutant proteins. In a recent study we showed a functional association between...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 08c4a869-9556-5166-a7f9-7770dc9a30f0
DOI: 10.21203/rs.3.rs-139718/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Targeted Immune Epitope Prediction to HHLA2 and MAGEB5 Protein Variants as Therapeutic Approach to Related Viral Diseases.DOI 10.21203/rs.3.rs-139718/v1Read

Targeted immune epitope prediction to HHLA2 and MAGEB5 protein variants as therapeutic approach to related viral diseases.Semantic proximity Read

Human endogenous retrovirus-H long terminal repeat-associating 2: The next immune checkpoint for antitumour therapySemantic proximity Read

Identification of immunotherapeutic epitope of E5 protein of human papillomavirus-16: An in silico approachSemantic proximity Read

In silico Antibody-Peptide Epitope prediction for Personalized cancer therapySemantic proximity Read

The Cancer Epitope Database and Analysis Resource: A Blueprint for the Establishment of a New Bioinformatics Resource for Use by the Cancer Immunology Community.Semantic proximity Read

HLA ligandome tumor antigen discovery for personalized vaccine approachSemantic proximity Read

Characterization of a new anti-LAG3 monoclonal for immuno-oncologySemantic proximity Read

Anti-MDA5 monoclonal antibodies from patients with dermatomyositis - B cell characteristics and differential targeting of the helicase domainsSemantic proximity Read

Somatically mutated regions of immunoglobulin on human B-cell lymphomas code for peptides that bind to autologous major histocompatibility complex class I, providing a potential target for cytotoxic T cells.Semantic proximity Read

HERV-derived epitopes represent new targets for T-cell based immunotherapies in ovarian cancerSemantic proximity Read

Characterization of Human Leukocyte Antigen (HLA) Proteins with Integrated Immunopeptidomics and Proteomics Approach.Semantic proximity Read

Identification of human leukemia antigen A*0201-restricted epitopes derived from epidermal growth factor pathway substrate number 8.Semantic proximity Read