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Artesunate mitigates acute pancreatitis by enhancing acinar zymophagy via modulating the NRF2-p62-Keap1 loop

2025-08-01

Abstract excerpt

<h4>Background: </h4> and Purpose:  Pancreatic zymophagy is a selective form of autophagy responsible for eliminating activated trypsinogen during acute pancreatitis (AP), and has emerged as a potential therapeutic target. However, the upstream regulatory mechanisms of zymophagy activation and the therapeutic potential of modulating zymophagy remain poorly understood. This study aimed to investigate the mechanisms...

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Literature Corpus work
08bbad21-7cb7-5011-ba40-c2ca108f9e9a
DOI
10.22541/au.175404080.04917407/v1
Open publication

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Artesunate mitigates acute pancreatitis by enhancing acinar zymophagy via modulating the NRF2-p62-Keap1 loopDOI 10.22541/au.175404080.04917407/v1
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