Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Unravelling the Role of PANoptosis in Liver Diseases: Mechanisms and Therapeutic Implications

21 Mar 2025

Abstract excerpt

PANoptosis is a multimodal form of cell death that involves inflammatory, apoptotic, and necroptotic pathways, playing a key role in the development of liver diseases. This article first outlines the definition and characteristics of PANoptosis, and then explores its mechanisms of action in different types of liver diseases, including acute liver injury, liver failure, metabolic dysfunction-associated fatty liver...

Topics

Join the communities discussing this publication.

Circular RNAs in diseases
Inflammasome and immune disorders
Liver Disease Diagnosis and Treatment

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 40116786
DOI: 10.1111/liv.70000

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Unravelling the Role of PANoptosis in Liver Diseases: Mechanisms and Therapeutic ImplicationsPMID 40116786Read ↗

PANoptosis-like death in acute-on-chronic liver failure injurySemantic proximity Read ↗

PANoptosis in cancer, the triangle of cell deathSemantic proximity Read ↗

PANoptosis: Novel insight into regulated cell death and its potential role in cardiovascular diseases (Review)Semantic proximity Read ↗

Do PANoptosis like cell death exist in Acute-on-chronic liver failure? Evidence from literature mining study, bioinformatics analyses and experimental researchSemantic proximity Read ↗

The Ways to Die: Cell Death in Liver PathophysiologySemantic proximity Read ↗

Programmed cell death in alcohol-associated liver diseaseSemantic proximity Read ↗

The Role of Autophagy in Liver Diseases: Mechanisms and Potential Therapeutic TargetsSemantic proximity Read ↗

Inhibition of Zbp1- PANoptosome-mediated PANoptosis effectively attenuates acute pancreatitisSemantic proximity Read ↗

Cell Death and Liver DiseaseSemantic proximity Read ↗

Inhibition of Zbp1-PANoptosome-mediated PANoptosis effectively attenuates acute pancreatitisSemantic proximity Read ↗

Distinct Types of Cell Death and Implications in Liver Diseases: An Overview of Mechanisms and ApplicationSemantic proximity Read ↗

Exploring the Multifaceted Landscape of MASLD: A Comprehensive Synthesis of Recent Studies, from Pathophysiology to Organoids and BeyondSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.