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Pancreatic Stellate Cells and the Targeted Therapeutic Strategies in Chronic Pancreatitis

22 Jul 2023

Abstract excerpt

Chronic pancreatitis (CP) is a disease characterized by inflammatory recurrence that accompanies the development of pancreatic fibrosis. As the mystery of CP pathogenesis is gradually revealed, accumulating evidence suggests that the activation of pancreatic stellate cells (PSCs) and the appearance of a myofibroblast-like phenotype are the key gatekeepers in the development of CP. Targeting PSCs to prevent their...

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PMID: 37513458
DOI: 10.3390/molecules28145586

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