Article
Tracking microbial evolution in the human gut using Hi-C
2019-03-31
Abstract excerpt
Despite the importance of horizontal gene transfer for rapid bacterial evolution, reliable assignment of mobile genetic elements to their microbial hosts in natural communities such as the human gut microbiota remains elusive. We used Hi-C (High-throughput chromosomal conformation capture), coupled with probabilistic modeling of experimental noise, to resolve 88 strain-level genomes of distal gut bacteria from two...
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Identifiers and source
- Literature Corpus work
- 08b9f8f3-75f3-57e5-8209-c25f21c014ab
- DOI
- 10.1101/594903