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A cryptic plasmid is among the most numerous genetic elements in the human gut

1 Feb 2024

Abstract excerpt

Plasmids are extrachromosomal genetic elements that often encode fitness-enhancing features. However, many bacteria carry "cryptic" plasmids that do not confer clear beneficial functions. We identified one such cryptic plasmid, pBI143, which is ubiquitous across industrialized gut microbiomes and is 14 times as numerous as crAssphage, currently established as the most abundant extrachromosomal genetic element in...

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PMID: 38428395
DOI: 10.1016/j.cell.2024.01.039

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