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Screening of Cellular Senescence (CS) Related Genes as Biomarkers and Therapeutic Targets for Glioblastoma (GBM) by Integrated Machine Learning (IML)

2025-08-24

Abstract excerpt

Glioblastoma (GBM) is an aggressive brain tumor with limited prognostic biomarkers and therapeutic targets. This study applied an integrated machine learning (IML) framework to discover cellular senescence (CS)-related gene biomarkers and candidate therapeutic targets in GBM. Using Gene Expression Omnibus (GEO) training and validation cohorts, 113 machine learning models across 11 algorithms were integrated to pin...

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Identifiers and source

Literature Corpus work
08493da3-d813-5133-9344-911ce766bc49
DOI
10.1101/2025.08.19.670890
Open publication

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Screening of Cellular Senescence (CS) Related Genes as Biomarkers and Therapeutic Targets for Glioblastoma (GBM) by Integrated Machine Learning (IML)DOI 10.1101/2025.08.19.670890
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