Article
Genetic characterisation of Malawian pneumococci prior to the roll-out of the PCV13 vaccine using a high-throughput whole genome sequencing approach.
PloS one - 1 Jan 2012
Everett Dean B, Cornick Jennifer, Denis Brigitte, Chewapreecha Claire, Croucher Nicholas, Harris Simon, Parkhill Julian, Gordon Stephen, Carrol Enitan D, French Neil, Heyderman Robert S, Bentley Stephen D
Abstract excerpt
BACKGROUND: Malawi commenced the introduction of the 13-valent pneumococcal conjugate vaccine (PCV13) into the routine infant immunisation schedule in November 2011. Here we have tested the utility of high throughput whole genome sequencing to provide a high-resolution view of pre-vaccine pneumoc...
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