Article

Isolation of telomerelike sequences from Cryptococcus neoformans and their use in high-efficiency transformation.

1992-06-01

Abstract excerpt

Development of a transformation system for the fungal human pathogen Cryptococcus neoformans is an important prerequisite for the identification of genes involved in virulence. It has previously been reported that low-efficiency transformation can be achieved by using the cloned C. neoformans URA5 gene and ura5 mutants. The introduction of linearized URA5 vectors into C. neoformans resulted in unstable transforman...

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Literature Corpus work: 080794cb-08a9-5060-a743-9044b4698462
DOI: 10.1128/mcb.12.6.2777

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