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A Modular Synthetic Hydrogel with Cell-scale Micropores Modulates Osteocyte-like Morphogenesis and Osteogenic Differentiation <i>In Vitro</i>

2026-08-04

Abstract excerpt

One crucial step during early osteogenesis is the embedding of osteoblasts within a collagen-rich extracellular matrix (osteoid), where they subsequently differentiate into a functional network of osteocytes. However, reconstructing 3D osteocyte networks in vitro remains a major challenge. We recently developed a synthetic microporous hydrogel to support the in vitro culture of 3D bone cell networks. Although ma...

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Literature Corpus work
07d96182-0afe-566c-8860-f2aff36ad7a0
DOI
10.64898/2026.08.04.742693
Open publication

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A Modular Synthetic Hydrogel with Cell-scale Micropores Modulates Osteocyte-like Morphogenesis and Osteogenic Differentiation <i>In Vitro</i>DOI 10.64898/2026.08.04.742693
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