Article
Highly porous polycaprolactone microspheres for skeletal repair promote a mature bone cell phenotype in vitro.
Journal of materials chemistry. B - 20 Nov 2024
Paterson Thomas E, Owen Robert, Sherborne Colin, Bahmaee Hossein, Harding Amy L, Green Nicola H, Reilly Gwendolen C, Claeyssens Frederik
Abstract excerpt
Improving our ability to treat skeletal defects is a critical medical challenge that necessitates the development of new biomaterials. One promising approach involves the use of degradable polymer microparticles with an interconnected internal porosity. Here, we employed a double emulsion to generate such round microparticles (also known as microspheres) from a polycaprolactone-based polymerised high internal...
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