Article

Synthetic Biodegradable Void-forming Hydrogels for <i>In Vitro</i> 3D Culture of Functional Human Bone Cell Networks

2023-10-25

Abstract excerpt

Generating 3D bone cell networks in vitro that accurately mimic the dynamic process of osteoblast embedding during early bone formation poses a significant challenge. Herein, we report a synthetic biodegradable macroporous hydrogel for efficient formation of 3D networks from human primary cells, analysis of cell-secreted extracellular matrix (ECM) and microfluidic integration. Using polymerization-induced phase s...

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Literature Corpus work: 4f1c71cb-1d20-5135-adea-cad56fdca5a6
DOI: 10.1101/2023.10.23.563580

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