Article

Integrating Ambient Mass Spectrometry Imaging and Spatial Transcriptomics on the Same Cancer Tissues to Identify Gene-Metabolite Correlations

2024-12-21

Abstract excerpt

The combination of spatial metabolomics and spatial transcriptomics can reveal powerful connections between gene expression and metabolism in heterogeneous tissues, but section-to-section variability can convolute data integration. We present a novel method combining Desorption Electrospray Ionization Mass Spectrometry Imaging spatial metabolomics and spatial transcriptomics on the same tissue sections. We demonst...

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Literature Corpus work: 07a6bba5-6991-5061-ab8c-f5fdbaf712a2
DOI: 10.1101/2024.12.20.626670

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