Article

Explainable AI identifies H3K18ac as a new marker of active enhancers

2026-06-11

Abstract excerpt

Enhancers are non-coding regions of DNA that regulate gene transcription, yet the mechanisms underlying enhancer activity remain incompletely understood. Despite extensive experimental and computational efforts, we still lack accurate enhancer maps in many human cells, tissues and disease contexts. Here, we developed several Artificial Intelligence (AI) models (Convolutional Neural Networks (CNN), XGBoost, Logisti...

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Literature Corpus work: 07903746-53f2-5a53-93c4-0786dda82388
DOI: 10.64898/2026.06.09.731088

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