Article

PGC1α and Exercise Adaptations in Zebrafish

2018-12-07

Abstract excerpt

<h4>ABSTRACT</h4> Fish species display huge differences in physical activity ranging from lethargy to migration of thousands of miles, making them an interesting model to identify determinants of physical fitness. Here, we show a remarkable plasticity of zebrafish in response to exercise and induction of PGC1α (encoded by PPARGC1A ), a dominant regulator of mitochondrial biogenesis. Forced expression of human P...

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Literature Corpus work: dc68f5f5-01a9-54f7-b590-7a15f3de0694
DOI: 10.1101/483784

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