Back to search

Article

Delayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscle

2025-03-18

Abstract excerpt

<title>Abstract</title> <p>Exercise is fundamental to healthy aging, yet the degree to which it mitigates age-related molecular changes and how varying physical fitness levels influence the molecular response to exercise with age remain unclear. To address this, we performed transcriptomics, lipidomics, and metabolomics on skeletal muscle of young and older adults with differing physical function, both before and...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
156c285f-b6fa-5ed8-a58f-e5300bfd96fe
DOI
10.21203/rs.3.rs-6074097/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Delayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscleDOI 10.21203/rs.3.rs-6074097/v1
Exercise is associated with younger methylome and transcriptome profiles in human skeletal muscleSemantic proximity
Exercise is associated with younger methylome and transcriptome profiles in human skeletal muscleSemantic proximity
Skeletal Muscle Transcriptomic Comparison between Long-Term Trained and Untrained Men and WomenSemantic proximity
Age-related changes in human skeletal muscle transcriptome and proteome are more affected by chronic inflammation and physical inactivity than primary agingSemantic proximity
Age‐related changes in human skeletal muscle transcriptome and proteome are more affected by chronic inflammation and physical inactivity than primary agingSemantic proximity
Temporal dynamics of the multi-omic response to endurance exercise training across tissuesSemantic proximity
Differential response trajectories to acute exercise in blood and muscleSemantic proximity
Differential genomic responses in old vs. young humans despite similar levels of modest muscle damage after resistance loadingSemantic proximity
Exercise mitigates age-related metabolic diseases by improving mitochondrial dysfunctionSemantic proximity
Effects of exercise on cellular and tissue agingSemantic proximity
Molecular Choreography of Acute ExerciseSemantic proximity
Proteomics of skeletal muscle agingSemantic proximity
Select a neighboring publication to make it the new centre.