Article

Altered Potassium Channels in Pancreatic Ductal Adenocarcinoma: Mechanisms, Implications, and Therapeutic Opportunities

2026-05-20

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal human malignancies, characterized by late diagnosis, aggressive metastatic behavior, and profound resistance to current therapies. Ion channels are increasingly recognized as active participants in oncogenesis, challenging the historic view of cancer as solely a genetic and biochemical disease. Emerging evidence has established that potassium (...

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Literature Corpus work: 0767b6c4-88aa-58fd-a76b-b305140d3fa8
DOI: 10.20944/preprints202605.1339.v1

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