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Roles of voltage‑gated potassium channels in the maintenance of pancreatic cancer stem cells

12 Aug 2021

Abstract excerpt

The targeting of membrane proteins that are activated in cancer stem cells (CSCs) represents one of the key recent strategies in cancer therapy. The present study analyzed ion channel expression profiles and functions in pancreatic CSCs (PCSCs). Cells strongly expressing aldehyde dehydrogenase 1 family member A1 (ALDH1A1) were isolated from the human pancreatic PK59 cell line using fluorescence‑activated cell...

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PMID: 34414448
DOI: 10.3892/ijo.2021.5256

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