Article
Ion Channels in Cancer: Are Cancer Hallmarks Oncochannelopathies?
Physiological reviews - 1 Apr 2018
Prevarskaya Natalia, Skryma Roman, Shuba Yaroslav
Abstract excerpt
Genomic instability is a primary cause and fundamental feature of human cancer. However, all cancer cell genotypes generally translate into several common pathophysiological features, often referred to as cancer hallmarks. Although nowadays the catalog of cancer hallmarks is quite broad, the most common and obvious of them are 1) uncontrolled proliferation, 2) resistance to programmed cell death (apoptosis), 3)...
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