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Impact of intracellular ion channels on cancer development and progression

11 Jun 2016

Abstract excerpt

Cancer research is nowadays focused on the identification of possible new targets in order to try to develop new drugs for curing untreatable tumors. Ion channels have emerged as "oncogenic" proteins, since they have an aberrant expression in cancers compared to normal tissues and contribute to several hallmarks of cancer, such as metabolic re-programming, limitless proliferative potential, apoptosis-resistance,...

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PMID: 27289382
DOI: 10.1007/s00249-016-1143-0

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