Article

A gene program dictionary of human cells

2025-10-30

Abstract excerpt

Defining all human cell types and their roles in health and disease is a central goal of biology. Single-cell RNA sequencing has enabled the construction of organ-specific cell atlases, but building a comprehensive organism-wide atlas spanning multiple organs remains challenging due to batch effects, study biases, and inter-organ complexity. Here, we present Gene Program Dictionary (GPD), a framework that leverage...

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Literature Corpus work: 076739dd-a581-5f68-8ae1-4e462832eb8c
DOI: 10.1101/2025.10.29.685322

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