Article

Molecular mechanisms regulating the G2 checkpoint induced after DNA damage

2006-01-01

Abstract excerpt

The checkpoint kinase (chk) 1 is an essential component of the DNA damage checkpoint acting as the effector of the DNA damage to block the cell cycle at the G2-M transition. The studies reported here were aimed at elucidating the molecular mechanisms regulating the G2 checkpoint after DNA damage and at investigating Chk1 as a potential therapeutic target for new cancer treatments. The promoter region of the human...

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Identifiers and source

Literature Corpus work: 07195f38-42b6-5cdc-8301-7ca17a0c7690
DOI: 10.21954/ou.ro.0000fe5b

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