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Article

The Chk2 protein kinase.

DNA repair - 1 Jan 2000

Ahn Jinwoo, Urist Marshall, Prives Carol

Abstract excerpt

Checkpoint kinase 2 (Chk2) is a multifunctional enzyme whose functions are central to the induction of cell cycle arrest and apoptosis by DNA damage. Insight into Chk2 has derived from multiple approaches. Biochemical studies have addressed Chk2 structure, domain organization and regulation by phosphorylation. Extensive work has been done to identify factors that recognize and respond to DNA damage in order to...

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Source

Identifiers

PMID: 15279791
DOI: 10.1016/j.dnarep.2004.03.033

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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