Article
Albendazole ameliorates aerobic glycolysis in myofibroblasts to reverse pulmonary fibrosis
2023-12-06
Abstract excerpt
<h4>Background: </h4> Idiopathic pulmonary fibrosis (IPF) is a chronic and lethal lung disorder for which effective treatments remain limited. Recent investigations revealed a potential link between altered glucose metabolism and the activation of fibroblasts, the key cells responsible for generating and depositing extracellular matrix proteins within the lung interstitium during IPF development. Method In this s...
Topics
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- Chronic Obstructive Pulmonary Disease (COPD) Research
- Histone Deacetylase Inhibitors Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Lung Cancer Treatments and Mutations
- Medical Imaging and Pathology Studies
- Mesenchymal stem cell research
- Peptidase Inhibition and Analysis
- Systemic Sclerosis and Related Diseases
Identifiers and source
- Literature Corpus work
- 06ed0512-059a-5a9e-830e-0f8dcec3e494
- DOI
- 10.21203/rs.3.rs-3690679/v1
