Article
A noble TGFβ biogenesis inhibitor exhibits both potent anti-fibrotic and anti-inflammatory capabilities
2019-09-16
Abstract excerpt
<h4>Abstracts</h4> Idiopathy pulmonary fibrosis (IPF) is an intractable and fatal human disorder. Our previous study showed that eupatilin exerted a potent anti-fibrotic effect on both in vitro fibrogenesis and bleomycin-induced lung fibrosis model (BLM). Subsequently, an analog called ONG41008 had been identified as a more potent anti-fibrotic than eupatilin and also showed a potent anti-inflammatory capability...
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Identifiers and source
- Literature Corpus work
- 6c11d3e4-46db-508f-84ff-30c803ce3e85
- DOI
- 10.1101/770404