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Comprehensive analysis of the basement membrane in lung adenocarcinoma by bulk and single-cell sequencing analysis

1 Jan 2023

Abstract excerpt

The basement membrane (BM), as a critical component of the extracellular matrix, plays a role in cancer progression. However, the role of the BM in lung adenocarcinoma (LUAD) remains unclear. Methods: A total of 1383 patients from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) cohorts were enrolled in the study, and BM-related differentially expressed genes (BM-DEGs) were screened using weighted...

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PMID: 37325048
DOI: 10.7150/jca.83407

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