Article

B cell-extrinsic and intrinsic factors linked to early immune repletion after anti-CD20 therapy in patients with Multiple Sclerosis of African Ancestry

2025-03-10

Abstract excerpt

In prior investigations, we identified patients of African ancestry (AA) with Multiple Sclerosis (MS) who displayed more rapid B-cell repopulation after treatment with anti-CD20 monoclonal antibodies. In this study, we explored immunologic, serum drug monitoring, and genetic factors that may contribute to a faster rate of B-cell repletion in AA patients with MS, with comparisons to those with usual repletion patte...

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Literature Corpus work: 066d7231-b0a9-5b62-ad82-7092def8f8a3
DOI: 10.1101/2025.03.05.25321882

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B cell-extrinsic and intrinsic factors linked to early immune repletion after anti-CD20 therapy in patients with Multiple Sclerosis of African AncestryDOI 10.1101/2025.03.05.25321882Read

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