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Twin study dissects CXCR3+ memory B cells as non-heritable feature in multiple sclerosis

25 Mar 2024

Abstract excerpt

Background In multiple sclerosis (MS), B cells are considered main triggers of the disease, likely as the result of complex interaction between genetic and environmental risk factors. Studies on monozygotic twins discordant for MS offer a unique way to reduce this complexity and reveal discrepant subsets. Methods In this study, we analyzed B cell subsets in blood samples of monozygotic twins with and without MS...

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PMID: 38531361
DOI: 10.1016/j.medj.2024.02.013

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