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Integration of single-cell and bulk transcriptome analyses unravels a macrophage-based gene signature for prognostication and treatment in triple-negative breast cancer

2023-08-30

Abstract excerpt

<title>Abstract</title> <p>Objective As a dominant component within the tumor microenvironment, macrophages exert an essential role in almost all aspects of triple-negative breast cancer (TNBC). This work explored macrophage-associated signature genes for prognostication and treatment for TNBC. Methods Single-cell (GSE180286) and bulk transcriptome profiles (TCGA-TNBC, GSE96058 and GSE45255) were analyzed by ex...

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Literature Corpus work
140ed4a1-e6ca-5a75-a5bb-003ce7a37ce8
DOI
10.21203/rs.3.rs-3262118/v1
Open publication

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Integration of single-cell and bulk transcriptome analyses unravels a macrophage-based gene signature for prognostication and treatment in triple-negative breast cancerDOI 10.21203/rs.3.rs-3262118/v1
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