Article

Immunophenotyping of HER4/YAP axis in breast cancer brain metastasis

2020-01-31

Abstract excerpt

Brain metastasis (BrM) is a devastating diagnosis for patients with breast cancer. Identification of immunophenotypical features specific to BrM is crucial for developing effective new therapeutic interventions. Yes-associated protein (YAP) mediates downstream effects of the neuregulin receptor, HER4, on breast cancer cell proliferation in vitro . HER4 is frequently over-expressed in BrM, but the relationship wit...

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Literature Corpus work: 06403a77-5ce2-571e-a512-5794342f91f7
DOI: 10.1101/2020.01.29.924118

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