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An expanded proteomic survey of the human parasite <i>Leishmania major</i> focusing on changes in null mutants of the Golgi GDP-Mannose/Fucose/Arabino <i>pyranose</i> transporter <i>LPG2</i> or the mitochondrial fucosyltransferase <i>FUT1</i>

2022-10-30

Abstract excerpt

<h4>ABSTRACT</h4> The trypanosomatid protozoan parasite Leishmania has a significant impact on human health globally. Understanding the pathways associated with virulence within this significant pathogen is critical for identifying novel vaccination and chemotherapy targets. Within this study we leverage an ultradeep proteomic approach to improve our understanding of two virulence associated genes in Leishmania...

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Literature Corpus work
063581b3-09ce-5ba9-9e5c-b5fa316ebc22
DOI
10.1101/2022.10.29.514353
Open publication

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An expanded proteomic survey of the human parasite <i>Leishmania major</i> focusing on changes in null mutants of the Golgi GDP-Mannose/Fucose/Arabino <i>pyranose</i> transporter <i>LPG2</i> or the mitochondrial fucosyltransferase <i>FUT1</i>DOI 10.1101/2022.10.29.514353
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