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Article

Post‐translational modification of cellular proteins during <b><i>Leishmania donovani</i></b> differentiation

8 Apr 2008

Abstract excerpt

The pathogenic intracellular parasites Leishmania donovani cycle between sand fly gut and the human macrophage phagolysosome, differentiating from extracellular promastigotes to intracellular amastigote forms. Using isobaric tagging for relative and absolute quantifications (iTRAQ/LC-MS/MS) proteomic methodology, we recently described the ordered gene expression changes during this process. While protein...

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PMID: 18398879
DOI: 10.1002/pmic.200701043

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