Article
Primary Cilia in Brain Development and Diseases.
The American journal of pathology - 1 Jan 2018
Youn Yong Ha, Han Young-Goo
Abstract excerpt
The primary cilium, a sensory appendage that is present in most mammalian cells, plays critical roles in signaling pathways and cell cycle progression. Mutations that affect the structure or function of primary cilia result in ciliopathies, a group of developmental and degenerative diseases that affect almost all organs and tissues. Our understanding of the constituents, development, and function of primary cilia...
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