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Article

A short course of antibiotics selects for persistent resistance in the human gut

2023-10-13

Abstract excerpt

<title>Abstract</title> <p>Understanding the relationship between antibiotic use and the evolution of antimicrobial resistance is vital for effective antibiotic stewardship, yet animal models and in vitro experiments poorly replicate real-world conditions. To elucidate how resistance evolves in vivo, we exposed 60 human subjects to ciprofloxacin and used longitudinal stool samples and a new computational method t...

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Literature Corpus work
05de25de-5b28-5b98-92ec-99f012d63bf4
DOI
10.21203/rs.3.rs-3399159/v1
Open publication

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A short course of antibiotics selects for persistent resistance in the human gutDOI 10.21203/rs.3.rs-3399159/v1
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