Article

A short course of antibiotics selects for persistent resistance in the human gut

2023-09-05

Abstract excerpt

Understanding the relationship between antibiotic use and the evolution of antimicrobial resistance is vital for effective antibiotic stewardship, yet animal models and in vitro experiments poorly replicate real-world conditions. To elucidate how resistance evolves in vivo , we exposed 60 human subjects to ciprofloxacin and used longitudinal stool samples and a new computational method to assemble genomes for 56...

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Literature Corpus work: a3f02090-230b-5030-bab8-930d72f68c33
DOI: 10.1101/2023.09.04.556257

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