Article

Glycated ɑ1-Antitrypsin Involvement in Impaired Wound Healing: In- Vivo and In-Vitro Models

2024-10-14

Abstract excerpt

<title>Abstract</title> <p>Impaired wound healing causes considerable morbidity among patients with diabetes. Human ɑ1-antitrypsin (hAAT) directs inflammation in injured tissues toward resolution. Upon glycation, gly-hAAT loses anti-proteolytic activity, but whether it fails to modulate inflammation and to promote wound repair is unknown. <bold>Objective</bold>: Explore the impact of clinical-grade hAAT on wound...

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Literature Corpus work: 05bc5334-df1f-5611-b029-dea9f59eb228
DOI: 10.21203/rs.3.rs-4931520/v1

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