Article
The synergism of age and db/db genotype impairs wound healing.
Experimental gerontology - 1 Jun 2007
Brem Harold, Tomic-Canic Marjana, Entero Hyacinth, Hanflik Andrew M, Wang Vincent M, Fallon John T, Ehrlich H Paul
Abstract excerpt
Both diabetes and advanced age have been implicated in delaying wound repair. However, the contribution of age alone has not been shown clinically to significantly impair the ability to heal. To determine the contribution of age and db/db genotype multiple wound healing parameters were determined in young db/db mice, aged db/db mice, age-matched non-db/db control and wild-type C57BL/6 mice. Biomechanical...
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