Article

β-Hydroxybutyrate elicits divergent metabolic responses between MCF-7 and T47D ER+ breast cancer cells under glucose restriction

2026-05-18

Abstract excerpt

<h4>Background</h4> The ketogenic diet is being explored as an adjuvant intervention in breast cancer because it lowers circulating glucose and elevates ketone bodies such as β-hydroxybutyrate (BHB), but how individual ER+ breast cancer subtypes adapt to these conditions remains poorly characterized. We examined metabolic responses to BHB supplementation under glucose restriction in two ER+ breast cancer cell lin...

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Literature Corpus work: 056b85c4-a2c6-5dad-a87d-d999b465c8bc
DOI: 10.64898/2026.05.14.725288

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