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Metabolic alterations and cellular responses to β-Hydroxybutyrate treatment in breast cancer cells

29 May 2024

Abstract excerpt

BACKGROUND: The ketogenic diet (KD), based on high fat (over 70% of daily calories), low carbohydrate, and adequate protein intake, has become popular due to its potential therapeutic benefits for several diseases including cancer. Under KD and starvation conditions, the lack of carbohydrates promotes the production of ketone bodies (KB) from fats by the liver as an alternative source of metabolic energy. KD and...

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PMID: 38812058
DOI: 10.1186/s40170-024-00339-1

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